Molecular Insight Pharmaceutica (NasdaqGM: MIPI) After Hours: 2.26 Up 0.76 (50.67%) 4:51pm ET
4:07PM Molecular Insight Pharmas' Onalta phase 2 data published in Journal of Clinical Oncology (MIPI) 1.97 +0.46 : Co announces results from a completed Phase 2 clinical trial of Onalta (Yttrium-90 edotreotide) have been published in the Journal of Clinical Oncology. Results from the Phase 2 clinical trial of 90 patients show that treatment with Onalta improved symptoms associated with metastatic carcinoid tumors. Patients enrolled in the Phase 2 clinical study suffered from malignant metastatic carcinoid tumors and were refractory to conventional treatment with the somatostatin analogue, octreotide. Y-90-edotreotide therapy resulted in objective tumor response or stable disease in 67 (74.4%) of 90 patients with metastatic carcinoid refractory to octreotide therapy. Median progression-free survival and overall survival were 16.3 and 26.9 months, respectively. Furthermore, there appeared to be a correlation with prolongation of the period of progression free survival in those patients who had durable diarrhea improvement.
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