Avid Bioservices Inc (CDMO)

[entdoc]

charlie3: side-effect profile appears good--acceptable. 6 serious adverse events were observed in 5 patients/26 in 868 doses, with 1 drug-related pulmonary embolism at the 3 mg/kg (highest) dose. The most common adverse events in >=15% of patients were: nausea, fatigue; headache, constipation, dizziness cough, dyspnea, anemia, and chest pain. Re. the pulmonary embolism, remember that blood clots are part and parcel of cancers since they tend to be "pro-thrombotic," and it is difficult to imagine an effective anti-cancer agent without side-effects. Because of sample size the side-effect profile might move either direction still, so...just so there isn't serious hair loss!