RegeneRx Biopharmaceuticals, Inc (RGN)

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8:56AM Regenerex Biopharam: Researchers report that Thymosin beta 4 improves neurological function after stroke (RGN) 0.62 : Co announces that a research team from the Henry Ford Hospital in Detroit, MI reported that Thymosin beta 4, administered to rats one day after embolic stroke, improved neurological functional outcome compared to control animals. Improvement in neurological function was measured at various time intervals over a seven week period and was statistically significant. An increase in remyelination of axons was observed in rats receiving Tb4 compared to control animals, likely due to an increased mobilization of oligodendrocyte progenitors that differentiate into mature myelin-producing oligodendrocytes. In cell culture, Tb4 treated neuronal progenitor cells isolated from normal and stroke rats demonstrated increased mRNA levels of epidermal growth factor receptor. This receptor has previously been shown to be a regulator of oligoprogenitor cell expansion and tissue regeneration in response to brain injury and further supports the role of Tb4 in stem cell-mediated tissue repair