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genisi

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genisi

Re: xrymd post# 90418

Wednesday, 02/10/2010 10:13:30 AM

Wednesday, February 10, 2010 10:13:30 AM

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ISIS/mipomersen

As in other mipomersen trials, elevations in liver transaminases were observed that were similar in magnitude and duration to those seen in other studies.

Liver tox will probably limit approval and use in broader indications beyond HoFH and perhaps HeFH.
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