AVAX Technologies Inc (AVXT)

[Zilla]

I almost bought it at .10 a few weeks ago but after doing some DD I decided not to. Can't remember why, but with it being up 100% from where I didn't buy before, I wouldn't touch it right now. I use to "chase" stocks when they ran up on heavy volume, but usually they fall the next day off of more heavy volume. The key is to find the gem before the run and with it being the end of 2009, I'd bet a lot of stocks will run up before dumping.
Another way to play is the bounce after a fall. Watch VION they just BK'd. I'd made some money when they fell a few months back off the bounce and I remember I liked what I'd learned from my DD back then. I'll wait til it's under .05-.005 range. Usually I'd wait longer, but I hesitated on buying 100,000 LJPC @ .05, I was waiting for .03, but it had good news and ran up to .30. It's fallen to .20 since and that's where I'd sold it a long time ago.
I think the reason certain stocks do this late in the year is because "listed" companies usually have BIG MONEY invested and they "run" it to get their cash out by getting newer investors to "chase" it. The end of the year will help with profits and tax losses. I've trimmed most of my portfolio down to about 6 stocks. I've had as many as over 30. I use to buy big name companies at a 100-1000 shares, but I made much more money when I got much more shares. I'll buy a few positions with 5000 shares to "check it out" but usually it's 25k-250k shares now. If you do enough DD that you "believe" then it becomes easier to "risk" investing more money to get bigger returns.
Good luck to you. :)