Biotech Values

[poorgradstudent]

IVUS:

There is also an outstanding question as to whether or not the results in IVUS are predictive.

This is a terribly noisy measurement, and many of the small trials relying on it have tried to use a single operator to conduct all the measurements.

Using a single operator to make measurements obviously won't fly in a 5000+ patient phase 3 trial. So it is reasonable to ask what real predictive value IVUS provides in translating phase 2 data to phase 3 mortality data.