Avid Bioservices Inc (CDMO)

[entdoc]

realist, you asked, "do you expect the next Bavi anti-cancer trial to be another phase II?" That question pales in importance compared to the fact that there will, in fact, be more Bavi trials, and hopefully many more. What is happening is the establishment of a technological base, or a platform, for continued anti-ps human trials. Interest in anti-ps is not limited to PPHM. PPHM simply as the undisputed lead in applying the technology safely to humans for human disease. We now know what anyone should have suspected, that short-term naked Bavi is not enough for sizable solid tumors, especially in an immune-depleted "salvage" population who have probably already had immunosuppressive drugs and advanced protein wasting, etc. Put another way, if side-effects had been considerable in this trial it might have really dampened forward momentum. We know that "armed" Bavi has not even been tried in a human population, and anyone can see it is sensible to proceed. That is huge. Establishing a broad-base of clinical safety and efficacy for a "new" technology is critical, and I believe PPHM has achieved that goal. For that reason a broader base of financial support will follow. Results of other Bavi clinical trials in progress will broaden the base, and I suspect that even if Phase II trials continue, so will investor interest. I still believe the company and the technology has a great future. Much better than any time in the past.