DNAprint Genomics (DNAG)

[mingwan0]

Bingo!

Biofontera's projects at the preclinical research stage include

Cathepsin inhibitors

Inhibitors for protease activated receptors

Inhibitors for sphingomyelinase

Kinase inhibitors

Biofrontera's projects at the preclinical development stage include

- 5-HT2B receptor inhibitor for migraine prophylaxis

Biofrontera's projects at the clinical development stage include

Histidine decarboxylase inhibitor (Phase II)

Skin cancer drug (Phase II, inlicensing deal currently closed)

DNAPrint's projects include

Ovanome - Taxol/Carboplatin efficacy

Statnome - Lipitor, Zocor, efficacy

Statnome Muscle - Lipitor, Zocor adverse myalgia response

Acenome - Enalapril, Lisinopril efficacy

Acenome Musc - Enalapril, Lisinopril adverse cough

Immunosuppressants - Sirolimus, Tacrolimus, Mycophenolate mofetil efficacy in transplant patients

Moffitt projects

1) Response of Metastatic Colorectal Cancer to Irinotecan/Capecitabine (Xeliri) and Oxaliplatin/Capecitabine (Xelox)

2) Melphalan and Topotecan (MT) efficacy for treatment of Multiple Myeloma

3) Cyclophosphamide efficacy

4) Organistron adverse events - post operative nausea and vomiting

5) Esophageal malignancy chemotherapy response - standard FDA treatment