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Sunday, October 03, 2004 11:18:58 PM
http://www.mpg.de/english/institutesProjectsFacilities/instituteChoice/neurologische_forschung/instP...
EU-funded project: Gene search towards the identification of novel therapeutical strategies against brain ischemia (StrokeGene)
Stroke and other manifestations of brain ischemia are common and devastating disorders, the outcome of which is largely regulated by specific genomic responses. StrokeGene, a research consortium sponsored by the 5th Framework Programme of the Europan Commission and co-ordinated by the Max Planck Institute, searches for such genes in clinically relevant experimental ischemia models. Brain regions with reversible and irreversible injury are identified and high-throughput gene expression profiling is carried out using digital expression pattern display (DEPD®) and automated DNA chip technology. Outcome specific genes are identified and tested for pathophysiological relevance. Based on this information, novel treatment strategies are designed and evaluated for therapeutic efficacy.
Partner: Biofrontera Pharmaceuticals, Laboratory of Physiology, ESPCI, Max Planck Institute for molecular Genetics, Pharmacology School of Pharmacy, University of Bradford, Dept. of Biomedical Sciences, Unversity of Padova, Dept. of Neuropathology, Medical Research Centre, Polish Academy of Sciences, Department of Cell and Molecular Biology, Karolinska Institute
http://www.brad.ac.uk/strokegene/
StrokeGene
An international research programme, funded by the European Commission, aiming to discover new treatments for stroke through a genomic approach.
-Max-Planck-Institute for Neurological Research (Cologne, Germany)
-Max-Planck-Institute for Molecular Genetics (Berlin, Germany)
-University of Bradford, Pharmacy (Bradford, Great Britain)
-Medical Research Centre, Neuropathology (Warsaw, Poland)
-Ecole Supérieure de Physique et de Chimie Industrielles de Paris (France)
-University of Padova, Biomedical Sciences (Padova, Italy)
-Karolinska Institute, Cell and Molecular Biology (Stockholm, Sweden)
-Biofrontera Pharmaceuticals (Leverkusen, Germany)
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