@Smitter - 9/16 Shares Owned My Calculations: 140,412,145
Raymond P. Warrell, Jr..................48,184,785
Cat Trail Private Equity Fund LLC...17,754,451
--667-1,2, 14159,
--Baker Brothers Life Sciences, L.P..16,968,279
BAM Opportunity Fund LP..............13,476,214
Loretta M. Itri...................................12,315,425
Tang Capital Partners, LP..............11,766,912
Arcus Ventures Fund.......................10,503,366
W. Lloyd Sanders..............................4,413,365
Gary Siegel.......................................2,942,134
Douglas G. Watson...............................695,858
Christopher Parios...............................695,698
Daniel D. Von Hoff...............................695,658
Boxer Capital LLC (Tavistock)..................??????
Rodman and Renshaw LLC.......................??????
Rockmore Investment Master Fund Ltd........??????
Cranshire Capital LP.................................??????
RRC Biofund LP........................................??????
Total Shares......................................140,412,145
Shares Outstanding 9/15/09...............169,684,485
Percent of Outstanding Shares...............82.75%
