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Post# of 252476
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Re: DewDiligence post# 82712

Friday, 08/21/2009 7:03:50 PM

Friday, August 21, 2009 7:03:50 PM

Post# of 252476
Cystic Fibrosis -

Shouldn’t VX-770/VX-809 be on your list?



Yes and no. I looked at 770 earlier and didn't put it in the list (and in fact forgot about it) because the frequency of the particular genetic defect it treats is very low (about 4% of CF patients - and yes, I have been inconsistent about filtering. My bad. C'est la vie.).

But I should have 809 on the list because the genetic defect it treats is the most common individual genetic variant in CF (at around 50% of CF population being at least heterozygous - although it varies widely based upon geographic location)

Tx again.

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