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Post# of 252983
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Alias Born 04/28/2004

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Thursday, 09/16/2004 1:09:17 PM

Thursday, September 16, 2004 1:09:17 PM

Post# of 252983
Interesting NEJM Question / Commentary that was brought to my attention by Biowatch.

Two independent groups cite observations in glioblastoma and NSCLC that patients responsive to Iressa tend to have cytoplasmic expression of EGF-R. It would be interesting if cytoplasmic expression becomes a validated biological finding in these tumours... it would have some consequences in the battle between small molecules and antibodies aimed at EGF-R.
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