Sunday, September 12, 2004 10:40:19 PM
http://jmg.bmjjournals.com/cgi/content/full/39/12/913
SNP S1103Y in the cardiac sodium channel gene SCN5A is associated with cardiac arrhythmias and sudden death in a white family
Journal of Medical Genetics 2002;39:913-915
S Chen1,2, M K Chung2, D Martin2, R Rozich2, P J Tchou2 and Q Wang1,2
1 Center for Molecular Genetics, Department of Molecular Cardiology, Lerner Research Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
2 Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Ancestry analysis (ANCESTRY 1.0) was performed for three family members in kindred QW1446 (II.1, II.3, and II.5 in fig 1A) by DNAPrint Genomics (Sarasota, FL). ANCESTRY 1.0 facilitates the estimation of biogeographical ancestry on three axes, Native American, West African, and European. In this analysis each subject was genotyped for 31 Ancestry Informative Markers. Using maximum likelihood, the individual ancestral proportions of these three populations in the resulting multilocus genotype was computed.10
http://www.lerner.ccf.org/moleccard/wang/
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