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Re: DewDiligence post# 79968

Friday, 06/26/2009 6:23:55 AM

Friday, June 26, 2009 6:23:55 AM

Post# of 252319

The cancer risk can be mitigated if Lantus is taken in conjunction with Acomplia.

So patients will commit suicide before they get cancer...
Seriously, I can see were the worry regarding cancer risk of Lantus comes from. Insulin analogues have different binding affinity for the type 1 insulin-like growth factor (IGF1R), and Lantus was the only one presenting a significant increase in affinity to IGF1R. IGF1R is a proliferation promoting receptor, and has been associated with cancer progression (it increases the aggressiveness of already transformed cells), but so far, neither IGF-I nor insulin were shown to cause malignant transformation and it would take more scientific publication to prove that Lantos stimulates cancer.

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