RespireRx Pharmaceuticals Inc (RSPI)

[erbse24448]

OT CNS 7056 PAION NeuroInv,
thanks for your answer. Here are some facts from a CNS 7056 study. I think they save a lot of time against Midazolam.

>>>Dose dependent sedation, with a rapid onset of effect, was observed after administration of CNS 7056 at doses of 0.05 mg/kg and higher. Doses of CNS 7056 (0.075 - 0.20 mg/kg) that induced peak sedation levels similar to or greater than those achieved with midazolam (0.075 mg/kg) showed a markedly shorter duration of sedative effect with recovery from sedation within approximately 10 minutes compared to approximately 40 minutes for midazolam. The peak sedative effect of CNS 7056 was reached within four minutes in these dose groups, with initial onset of sedation being observed after approximately one minute. For midazolam, the peak effect was reached after approximately 15 minutes. Duration and depth of sedation increased with higher doses of CNS 7056, while the recovery was still earlier as compared to midazolam. >>>

Have a nice day
Erbse