RespireRx Pharmaceuticals Inc (RSPI): It's not patient-to-patient variability,...

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Re: atheroprevent post# 25879

Wednesday, 05/20/2009 12:55:12 PM

Wednesday, May 20, 2009 12:55:12 PM

It's not patient-to-patient variability, but night-to-night variability in any given patient, that worries me.

Sleep can, among other things, be considered a homeostatic/allostatic process, embedded in feedback loops. Ampakines will be changing slow feedback to this system, and I think the response will be complicated, because of nonspecific ampakine effects.

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