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Re: bladerunner1717 post# 25654

Monday, 05/11/2009 2:22:08 PM

Monday, May 11, 2009 2:22:08 PM

Post# of 45304
Hi bladerunner, OT
they have a good management. I will see them in two weeks at the annual general meeting. Yes they have a nice pipeline. This is worth a search.
They have the wrong strategy by the last desmoteplase stroke trial with the Penumbra Proof.
With the new strategy Vascular occlusion they have a good chance between 3 and 9 hours.
More Information about stroke and desmoteplase in english and german:

http://www.erbse.vm-elsig.de/form/base/YaBB.pl?num=1217124088;start=all

My favorit is CNS 7056 . They have a POC and the Phase 2 studie is ready at end of this year. They have a peak sales from 500 - 1000 Millions. With a cooparation Paion can get 20% til 25%. Now they have a marketcap from 25 Millions.

Here the information about CNS 7056

About CNS 7056

CNS 7056 is a new short-acting sedative and general anesthetic that acts on GABAA receptors. The substance was added to PAIONs portfolio by acquiring CeNeS who in turn had acquired the substance from GlaxoSmithKline. CNS 7056 is a water-soluble, rapid and short-acting GABAA receptor modulator interacting with the benzodiazepine site. The clinical proof of concept study, reported in January 2009, showed that, after intravenous administration, CNS 7056 rapidly induces sedation. Importantly the sedative effects rapidly disappear after cessation of administration. The rapid offset of effect of the compound is due to its metabolism by esterase enzymes that are widely distributed throughout the body. Therefore it is anticipated that CNS 7056 can be clinically developed as a sedative agent for day case procedures, the induction and maintenance of anesthesia and ICU sedation. PAION initiated partnering discussions in parallel to the ongoing Phase II in order to accelerate the further development of CNS 7056 for territories outside Japan, where the compound is partnered to Ono Pharmaceuticals.

Paion is listed at the OTC. but there are no trades. You can trade them at the german xetra or at the frankfurt stock exchange. It is better you take a limit.
Hope this helps
Erbse
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