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Re: enemem post# 24825

Saturday, 04/04/2009 9:45:47 PM

Saturday, April 04, 2009 9:45:47 PM

Post# of 52265
<<Ampakines are broad-spectrum>>

That's not what Gary Lynch believes. There are subtypes of AMPA receptors, and different Ampakines have different profiles of activity--including varying degrees of waking/alerting impact. I agree that the insomnia question is a big one--but as I noted before, they've run Phase I studies where insomnia would have been an AE of interest.

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