Protokinetix's CONTROLLED LABORATORY TESTS >>
AAGP™ testing is conducted to international standards in outsourced research laboratories in North America and Europe.
All tests are designed to explore both the safety and effectiveness of AAGP™ when challenged to enhance the health and extend the life of cells.
AAGP™ STABILITY TESTS
AAGPs™ are tested for non-toxicity and stability.
AAGP™ molecules have remained stable when subjected to three tests:
pH ranging from a strong acid level of 1.8 (stronger than stomach acid) to a strong alkali level of 13.8. (the pH scale is calibrated from 1, highly acidic, to 14, highly alkali)
Enzymatic action using protease, which targets the amino acid bonds, and glycosidase, which targets the sugar molecules.
Temperatures ranging from -196°C (cryopreservation) to +37°C (body temperature).
AAGP™ TOXICITY TESTS >>
Cells that have been exposed to AAGP™ at low and high concentrations have remained viable. A common viability test used on cell cultures using trypan blue dye exclusion method has been used to show AAGP™ non-toxicity.
STRESS TESTS ON CELL LINES >>
Cell lines are selected for their high level of sensitivity.
Cell lines are also selected for their potential role in adding value in medical applications, enhancing health and extending life.
All tests are designed to explore how cells from different cell lines act biologically in the presence of AAGP™ when subjected to health and life threatening inflammatory stress conditions and agents.
Results Summary:
In every test the cells that were in the presence of AAGP™ had a higher survival and viability rate than the controls. The overall effect of AAGP™ is to protect, preserve and in some cases to repair. Anti-oxidant and anti-inflammatory effects appear to be at work. AAGP™ appears to enhance heath and extend cell life.
CELL LINES TESTED >>
Stem Cells (Human)
Whole Blood Cells
Blood Platelet Cells
Heart Tissue
Hela (Cancer) Cells
Kidney (KB and Vero) Cells
Adult Skin Fibroblast Cells
Heart Cells (Cardiac Myocites)
Liver Cells (Hepatocites)
Embryonic Skin Fibroblast Cells
Islet Cells (Pancreatic)
Stem Cells (Mouse)
STRESS CONDITIONS AND AGENTS >>
Temperature
· Temperatures ranging from -80° C to +37° C
UV-C Radiation
· This is harsh sterilizing radiation
· 254 Nanometer Wavelength
Oxidation
· Hydrogen Peroxide (H202)
· Powerful Oxidant
Starvation
· Serem Free Culture Media
· Food / Growth / Nutrients Factors (Fetal Bovine Serum) withheld
Inflammation
· Interleukin 1 Beta, a standard agent for stimulating inflammation in cell testing
*All of the above tests are also considered to cause inflammation
BIO-SCREENING CONTROL LAB TESTING >>
AAGP™ testing is conducted to international standards in outsourced research laboratories in North America and Europe.
All tests are designed to explore both the safety and effectiveness of AAGP™ when challenged to enhance the health and extend the life of cells.
AAGPs™ are tested for non-toxicity and stability.
