RespireRx Pharmaceuticals Inc (RSPI)

[neuroinv]

A couple of points: per patient cost is far higher than just sending a patient to a sleep lab for one night. They are going to send them three times, the first two to make sure that they have sleep apnea, and that the apnea episodes are similar in frequency each time. A patient whose apnea varies would muck up their results. This also means they will be running patients in the first one or two sleep lab nights who won't be eligible for the study itself--the third night, when patients get drug or placebo. It is also being run by a clinical research group, who gets paid to deal with patient entry, evaluation, data collection and blinding. Having a CRO at least doubles the cost based on my past experience--but if you dont have inhouse staff to run a trial, and Cortex doesn't, there aren't any options. I figure $10-20,000 per patient enrolled, plus some costs for the patients who are not enrolled but are assessed.

They might have the money to run the trial in and of itself--but they have to keep the lights until the trial is done--and if they lay everyone off, they won't have a company to run even if they have good data. There is the possibility they could run a few patients, see the blinded data shows a big change, and take the risk of unblinding and trying to do a deal based on that. But they cannot go into the trial assuming that. They have to assume that the trial goes the full duration, and that they then need the time to partner.

For this they need money.

Which I continue to believe they will get.

NeuroInvestment