DNAprint Genomics (DNAG)

[mingwan0]

We knew it was coming:

Eye colour: portals into pigmentation genes and ancestry.

Sturm RA, Frudakis TN. Eye colour: portals into pigmentation genes and ancestry. Trends Genet. 2004 Aug;20(8):327-32.

Institute for Molecular Bioscience, University of Queensland, Brisbane, Qld 4072, Australia.

Several recent papers have tried to address the genetic determination of eye colour via microsatellite linkage, testing of pigmentation candidate gene polymorphisms and the genome wide analysis of SNP markers that are informative for ancestry. These studies show that the OCA2 gene on chromosome 15 is the major determinant of brown and/or blue eye colour but also indicate that other loci will be involved in the broad range of hues seen in this trait in Europeans.