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apljack

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apljack

Re: mcbio post# 69436

Thursday, 12/04/2008 8:06:43 AM

Thursday, December 04, 2008 8:06:43 AM

Post# of 252706
McBio, Neutropenia could be a game stopper if it is severe enough and/or chronic enough. Many RA patients are old and weak, with already weakened immune systems, so I'm sure that there would be a concern about exposing these patients to a long-term therapy that has a 10% neutropenia side effect profile.

What will be an absolute game stopper is the number of agranulocytosis patients found in P3 trials, at least IMO.

aj
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