obviously experienced, scientifically...a lot of antisense experience...ergo Isis..
here is his first 20 papers from Pub Med
Adams MR, Nikkel AL, Donnelly-Roberts DL, Watt AT, Johnston JF, Cowsert LM, Butler M, Kroeger PE, Frost L, Curzon P, Decker MW, Bitner RS.
Abstract
In vitro and in vivo effects of an alpha3 neuronal nicotinic acetylcholine receptor antisense oligonucleotide.
Brain Res Mol Brain Res. 2004 Oct 22;129(1-2):67-79.
PMID: 15469883 [PubMed - indexed for MEDLINE]
2:
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Cavarretta IT, Mukopadhyay R, Lonard DM, Cowsert LM, Bennett CF, O'Malley BW, Smith CL.
Free Full Text
Reduction of coactivator expression by antisense oligodeoxynucleotides inhibits ERalpha transcriptional activity and MCF-7 proliferation.
Mol Endocrinol. 2002 Feb;16(2):253-70.
PMID: 11818499 [PubMed - indexed for MEDLINE]
3:
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Bennett CF, Cowsert LM.
Abstract
Application of antisense oligonucleotides for gene functionalization and target validation.
Curr Opin Mol Ther. 1999 Jun;1(3):359-71. Review.
PMID: 11713801 [PubMed - indexed for MEDLINE]
4:
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Cowsert LM.
No Abstract
Web alert. Antisense--from design to clinic.
Curr Opin Mol Ther. 2000 Jun;2(3):235. No abstract available.
PMID: 11249616 [PubMed - indexed for MEDLINE]
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Taylor V, Wong M, Brandts C, Reilly L, Dean NM, Cowsert LM, Moodie S, Stokoe D.
Free in PMC
5' phospholipid phosphatase SHIP-2 causes protein kinase B inactivation and cell cycle arrest in glioblastoma cells.
Mol Cell Biol. 2000 Sep;20(18):6860-71.
PMID: 10958682 [PubMed - indexed for MEDLINE]
6:
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Chen J, Wu W, Tahir SK, Kroeger PE, Rosenberg SH, Cowsert LM, Bennett F, Krajewski S, Krajewska M, Welsh K, Reed JC, Ng SC.
Free in PMC
Down-regulation of survivin by antisense oligonucleotides increases apoptosis, inhibits cytokinesis and anchorage-independent growth.
Neoplasia. 2000 May-Jun;2(3):235-41.
PMID: 10935509 [PubMed - indexed for MEDLINE]
7:
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Bennett CF, Cowsert LM.
No Abstract
Antisense oligonucleotides as a tool for gene functionalization and target validation.
Biochim Biophys Acta. 1999 Dec 10;1489(1):19-30. Review. No abstract available.
PMID: 10806994 [PubMed - indexed for MEDLINE]
8:
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Cowsert LM, Ohashi CT, Bhat B, Peoc'h D, Symons AM, Cook PD, Manoharan M.
No Abstract
MMI linkage modification increases potency and stability of H-ras antisense oligonucleotides.
Nucleosides Nucleotides. 1999 Jun-Jul;18(6-7):1383-4. No abstract available.
PMID: 10474224 [PubMed - indexed for MEDLINE]
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Sharpe CC, Dockrell ME, Scott R, Noor MI, Cowsert LM, Monia BP, Hendry BM.
Free Full Text
Evidence of a role for Ki-Ras in the stimulated proliferation of renal fibroblasts.
J Am Soc Nephrol. 1999 Jun;10(6):1186-92.
PMID: 10361856 [PubMed - indexed for MEDLINE]
10:
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Roberts ML, Cowsert LM.
Abstract
Interleukin-1 beta and reactive oxygen species mediate activation of c-Jun NH2-terminal kinases, in human epithelial cells, by two independent pathways.
Biochem Biophys Res Commun. 1998 Oct 9;251(1):166-72.
PMID: 9790925 [PubMed - indexed for MEDLINE]
11:
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Clark PR, Roberts ML, Cowsert LM.
Abstract
A novel drug screening assay for papillomavirus specific antiviral activity.
Antiviral Res. 1998 Feb;37(2):97-106.
PMID: 9588842 [PubMed - indexed for MEDLINE]
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Cowsert LM.
No Abstract
In vitro and in vivo activity of antisense inhibitors of ras: potential for clinical development.
Anticancer Drug Des. 1997 Jul;12(5):359-71. Review. No abstract available.
PMID: 9236852 [PubMed - indexed for MEDLINE]
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Renaud KJ, Cowsert LM.
Abstract
Characterization of human papillomavirus-11 mRNAs expressed in the context of autonomously replicating viral genomes.
Virology. 1996 Jun 1;220(1):177-85.
PMID: 8659110 [PubMed - indexed for MEDLINE]
14:
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Shadan FF, Cowsert LM, Villarreal LP.
Free in PMC
n-Butyrate, a cell cycle blocker, inhibits the replication of polyomaviruses and papillomaviruses but not that of adenoviruses and herpesviruses.
J Virol. 1994 Aug;68(8):4785-96.
PMID: 8035479 [PubMed - indexed for MEDLINE]
15:
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Cowsert LM.
No Abstract
Treatment of papillomavirus infections: recent practice and future approaches.
Intervirology. 1994;37(3-4):226-30. Review. No abstract available.
PMID: 7843933 [PubMed - indexed for MEDLINE]
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Steele C, Cowsert LM, Shillitoe EJ.
Free Full Text
Effects of human papillomavirus type 18-specific antisense oligonucleotides on the transformed phenotype of human carcinoma cell lines.
Cancer Res. 1993 May 15;53(10 Suppl):2330-7.
PMID: 7683572 [PubMed - indexed for MEDLINE]
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Cowsert LM, Fox MC, Zon G, Mirabelli CK.
Free in PMC
In vitro evaluation of phosphorothioate oligonucleotides targeted to the E2 mRNA of papillomavirus: potential treatment for genital warts.
Antimicrob Agents Chemother. 1993 Feb;37(2):171-7.
PMID: 8383937 [PubMed - indexed for MEDLINE]
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Baker TS, Newcomb WW, Olson NH, Cowsert LM, Olson C, Brown JC.
Free in PMC
Structures of bovine and human papillomaviruses. Analysis by cryoelectron microscopy and three-dimensional image reconstruction.
Biophys J. 1991 Dec;60(6):1445-56.
PMID: 1663794 [PubMed - indexed for MEDLINE]
19:
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Jin XW, Cowsert LM, Pilacinski WP, Jenson AB.
Free Full Text
Identification of L2 open reading frame gene products of bovine papillomavirus type 1 using monoclonal antibodies.
J Gen Virol. 1989 May;70 ( Pt 5):1133-40.
PMID: 2471804 [PubMed - indexed for MEDLINE]
20:
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Cowsert LM, Pilacinski WP, Jenson AB.
Abstract
Identification of the bovine papillomavirus L1 gene product using monoclonal antibodies.
Virology. 1988 Aug;165(2):613-5.
PMID: 2841806 [PubMed - indexed for MEDLINE]
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