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Sunday, 11/09/2008 2:11:33 PM

Sunday, November 09, 2008 2:11:33 PM

Post# of 19309
A leaf from the past...LEO could very well be in the same situation for DIC trials..

Bayer shelves drug produced from transgenic sheep. (Recombinant Proteins).
By Scott, Alex
Publication: Chemical Week
Date: Wednesday, July 16 2003

Bayer says it has shelved commercialization of its recombinant protein drug Alpha-1 Antitrypsin (recAAT) developed to treat lung disorders. PPL Therapeutics (Roslin, U.K.), which was to have manufactured the drug for Bayer using transgenic sheep, says it will shed up to 90% of its total staff, or about 130 positions, as a result of Bayer's withdrawal from the project.

Bayer says it cancelled the deal because of rising financial risks associated with the drug's clinical phase II trials, which FDA has asked to be repeated in parts because of a high drop out rate of trial
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