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Sunday, November 02, 2008 2:07:10 PM
Good question. The only reason I said late June/July is because that is the 12 month mark and the Avastin survival chart Mojo found has hash marks at 6 and 12 months making it easier to read at those points.
In fact I expect SK to give GA survival data updates at several points between now and mid summer, for example: the Dec 15 CC, the March 15 CC, AACR annual meeting on April 18 and ASCO on May 29. If the continuous dosing of Bavi (after chemo stops) is indeed yielding survival rates in the 90% to 100% range, SK won’t hide this fact. Believe it or not, SK and Mary Boyd are already working towards a Bavi BP deal and will beat the drums louder and louder as the Ph II data comes in during the first half of 2009.
By the way, Jazz’s post 26997 shows only PFS data. I think you may be confusing Progression-Free Survival with Overall Survival. Overall Survival is the sum of Progression-Free Survival plus Progression-Happened Survival. A tumor which was initially shrunk by Bavi from 100% to 30%, but then grows back to 50% of its original size, no longer counts as a PFS patient, even though the patient is stable and lives for another two years thanks to continuing weekly doses of Bavi.
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Pphmtoolong / Financing
What I “hear” is that the secured bank loan, i.e. the one that has been in the works for months now and repeatedly referenced by Mgmt., is still alive and has not been killed by the credit crisis. I also hear there is little to no anxiety within PPHM as to how the Company will stay funded.
What I guess, and this is speculation, is that their confidence comes from the AC and AV data they are seeing. IMO, they believe they can afford to wait another month or two to close the bank loan because (1) the credit markets will have returned to normal by January (or at least more so than today) and (2) Duke/Haynes data and India AC data will then be on the table and they expect to be in a much stronger negotiating position with a higher pps and a Duke/Gates/Chavi endorsement to back up their story.
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