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Post# of 252816
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Re: DewDiligence post# 65629

Friday, 09/12/2008 12:29:15 AM

Friday, September 12, 2008 12:29:15 AM

Post# of 252816
>>CEGE addendum: These are the worst results I’ve seen in a randomized, controlled cancer trial since TELK’s Telcyta.<<

Given that GVAX has shown a stellar safety profile in hundreds of patients over many years, my hypothesis is that the larger number of deaths in the GVAX + taxotere arm (67) compared to the taxotere monotherapy arm (47) is merely a statistical fluctuation, rather than an indication that GVAX + taxotere is bumping patients off.

A typical distribution function would give standard deviations of order sqrt(n), so the comparison is really something like

67 +/- 8 vs 47 +/- 7.

I think there is at least a 5% chance that the disagreement is simply statistical.

Anybody agree or disagree?

Implicit in my hypothesis is that GVAX provided no survival benefit in Vital-2.

micro

Life is an IQ test.

email: microcapfun@yahoo.com

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