Sunday, May 30, 2004 12:27:40 AM
Physical Profiling from Ancestry 2.0 Through Informatics:
DNA is commonly left at crime scenes, but until DNAPrint developed tests for doing so, no physical information could be reliably read from that DNA. In contrast to standard DNA testing, Ancestry 2.0 is expected to allow investigators to "paint" a partial physical profile from crime scene DNA, which could assist with the investigative process much like a human eye-witness could. For example, DNAPrint scientists and collaborators have used various versions of the Ancestry test to show correlation between European admixture and skin melanin content in African Americans (Shriver et al., Skin pigmentation, biogeographical ancestry and admixture mapping, Human Genetics (2003) 112: 387-399). A precise inference of skin tone will require a specific genetic test, which the Company is working on, but to allow forensics customers the immediate ability to make inferences of physical characteristics from Ancestry 2.0 results, the Company intends to provide forensic customers next quarter with access to a database of several hundred digital photographs from individuals who have taken part in the Company's validation studies. The customer would query the database to retrieve photographs for every individual whose profile falls within a specified range, such as "80% European + 20% sub-Saharan African +/- 10%", Through inspection, the customer would gauge variation in physical appearance associated with that range.
Thought this was interesting in that it provides concrete evidence of DNAPrint's involvement in the Shriver, et al study, something TonyTox had quite the problem with awhile back. Oh, and despite it's mention in this DNAPrint PR, DNAPrint was NOT specifically mentioned as a collaborator on the study:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12579416&...
Later,
W2P
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