jess,
re:"Haynes never mentions bavi"
Actually, Haynes mentions Bavi (as Bavi, Humanized Bavi, Tarvi, 3G4, 2AG4) several times in his recent patent applications. Bavi was also used in the work described in Haynes paper in the August issue of Virology.
Haynes used Bavi (2AG4) to bind and count the microparticles in patient # 6246. You previously tried to "dis" this work referring to Bavi as performing a minor role as a reagent, but the truth is Bavi played a role in proving how the exposed PS on microparticles is responsible for blunting the function of the immune cells that would ideally fight the virus, and that Bavi itself masks/binds the exposed PS.
In the WIPO patent applications Haynes discusses in great detail how exposed PS needs to be dealt with to give the immune system the chance to fight off the virus.
I conclude from these several patent applications, as well as the important paper in the August Virology (important because Haynes, besides corroborating the immunosuppressive function of exposed PS on macrophages, dendritic cells and resultant T cells, he also for the first time illustrates how exposed PS stifles antibody-producing B cells) that Haynes and the other scientists involved will be publishing the work which is discussed in the patent applications.
It seems obvious from his patent applications that anti-PS is a very promising therapeutic for those already infected with HIV,as well as anti-PS being an important goal of a vaccine immunogen.
Basically, Haynes, (CHAVI, and CAVD) seem to be focussing in on exposed PS as the immunosuppressive culprit, as well as anti-PS being the fix, and the only anti-PS mentioned in patent applications in the WIPO & USPTO databases, various recent Haynes CAVD conf. presentation abstracts, and the paper in Virology have been:
2AG4
3G4
Bavi
Tarvi
IS1
IS2
IS4
IS6
it's happening,
j
