Avid Bioservices Inc (CDMO)

[jazzbeerman]

jake, if you look at a particular Thorpe patent application a few years ago just before CHAVI/Gates CAVD got rolling, he goes into big detail into methods for generating mabs isolated from auto-immune patients to be used as therapy.

I posted it here when it came out.

Basically, Thorpe, (and Sophia Ran), were the first to really look into developing anti-phospholipid mabs AS THERAPY. It went (and still goes) against traditional immunological common sense. When it is finally accepted, (like for instance if some top doc like Bart Haynes ;) published a paper in a major journal about using anti-phospholipid mabs therapeutically, it will signify the beginning of the new paradigm.

While Thorpe and Ran were into therapeutics, others (like Pojen Chen), were primarily interested in understanding auto-immune disease, and what exactly makes anti-phospholipid abs pathogenic. They weren't really thinking about using anti-phospholipid mabs therapeutically.

Thorpe then listed all the ways to find them / produce them in a therapeutic patent application, which he filed a few years ago.



j