Friday, July 25, 2008 9:02:54 AM
re:"For me, the data out of Georgia and the recent announcements about how early after infection that HIV can compromise the immune system points why Bavi didn't perform as well in the HCV arena as was originally hoped."
Then you disagree with Haynes.
Haynes is proposing using anti-PS as HIV therapy.
He said it, not me.
He's basically saying it should work.
Why's he saying that?....
Haynes is saying any future successful vaccine needs to prevent immunosuppressive PS signaling.
Why's he saying that?....
Further, Haynes suggests that a good way to do it would be for the vaccine to induce anti-PS.
Why's he saying that?....
(That's rhetorical. You'd know why he's saying it if you were to read his papers and patent applications in their entirety).
Also, with regard to your statement above, it's funny you mention HCV in relation to this work... If you were to actually read the Haynes paper in the August Journal of Virology, you would see the differences- as discussed (and graphed!) by Haynes- illustrating the differences between the immunosuppressive PS-exposing microparticle aspect of the pathogenesis of HIV as compared to HCV and HBV.
j
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