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jazzbeerman

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jazzbeerman

Re: jazzbeerman post# 26069

Tuesday, 07/15/2008 1:10:04 PM

Tuesday, July 15, 2008 1:10:04 PM

Post# of 346614
3. Pojen Chen's team learns insights into antiphospholipid mab binding


In 2006 Chen's group learned WHY they stick to WHAT...

Specifically, why they stick to Beta-2-glycoprotein-I. (because of Arginine in certain places on the mab).

They also learned how to alter the mabs to change their binding specifics, to increase or decrease the mabs attraction to various phospholipids...

For instance, they changed IS4's binding characteristics...


http://www.jimmunol.org/cgi/content/full/177/3/1729



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