ProtoKinetix Inc (PKTX)

[Past and present]

Smaller is better, those darn "Daltons"... NATIVE AFGP >>
AFGP (Anti-Freeze Glycoprotein) is found in nature as a compound produced by some fish, insects, reptiles, bacteria and plants that enable survival in freezing temperatures.

AFGP acts to prevent ice crystals from spiking and rupturing cells, tissues and organs and thereby causing death. It also has a direct effect on cells by some undefined process.

There has been much scientific research done in an attempt to synthetically replicate AFGPs in research institutions because the protective properties of AFGPs could have commercial applications, primarily in food and crop preservation at freezing temperatures.

Scientific research prior to AAGP has focused on building a stable and more efficient compound with a strong bond.



AAGP™ INVENTION >>

AAGPs™ were invented by Dr. Geraldine-Castelot-Deliencourt and developed and protected by patents in partnership with the Institute for Scientific Application (INSA) of France. For her work in this area Dr. Castelot-Deliencourt was honored in 2006 with France’s highest award for scientific accomplishment – the Francinov Award.

AAGP™ is highly stable and not cytotoxic. The result is a molecule that is extremely small (about 580 Daltons) and can move through tissues and reach targeted cells to protect them from inflammatory and oxidative stresses and in some cases repair damage caused by these stresses.