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biophud

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biophud

Re: None

Wednesday, 05/21/2008 9:51:19 PM

Wednesday, May 21, 2008 9:51:19 PM

Post# of 4764
Pfizer's IGFR patent on their IgG2 antibody. Reduced immunogenicity (sp?). IMHO, if you are targeting cancer with an antibody to a cell surface receptor(s), then you want an IgG1 antibody.

http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=5&f=G&l=50&co1=AND&d=PTXT&s1=imclone&OS=imclone&RS=imclone

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