GTC Biotherapeutics (fka GTCB)

[jessellivermore]

IMHO.....Re Burns

My experience treating burns includes a tour in the RVN as a general surgeon at the USAH Saigon. Later during plastic surgery fellowship at U of Fla in Gainesville I managed the burn unit at Shands Hospital.

Serious burns are for the most part extensive full thickness (3rd degree) and are extremely complicated clinical situations involving many systems. The clinical situation is continually evolving over time. Initially the problems may be respiratory, related to inhalation smoke and released toxins,eg. wood smoke contains aldehydes, including formaldehyde. Fluid management is also critical. One of the most important functions of the skin is to conserve body fluids. When significant percentages of the skin is lost evaporative and other fluid loss increase dramatically and if untreated lead to dangerous dehydration or electrolyte imbalances. If the patient has not suscumbed then other long term problems occur, negative nitrogen balance, immune insufficency, sepsis,,,untill the patient has been skin grafted......This is a very condensed version..

Because of the complexity of clinical burns it is incorrect to think AT3 would be an overall cure for burns....It is certainly possible and very likely AT3 might be valuable in treating some of the situations that occur in burns,,eg. respiratory inflamation,, and sepsis.