Ocyan - do you have any thoughts on the minimum hazard ratios (if such a calculation is even possible) requiried to meet statistical significance I asked over on IV today (assuming I guess roughly 0.02 alpha and 220 to 240 patients at the interim and alpha of 0.04 at the final)? I am just trying to get a handle on what the HR hurdles required for success are at each look at the data. Much appreciation as always.
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