DNAprint Genomics (DNAG)

[mingwan0]

Dublin Molecular Medicine Centre

http://www.dmmc.ie/

DUBLIN MOLECULAR MEDICINE CENTRE (DMMC) represents a highly focused research partnership in the life sciences between the University College Dublin (UCD), Trinity College Dublin (TCD) and The Royal College of Surgeons in Ireland (RCSI). A network of affiliated hospitals provides the setting for accelerated translational bioscience.

http://www.dmmc.ie/programmes.htm

The Programme for Human Genomics (PHG)

The landmark completion of the Human Genome Project provides a unique resource for biomedical sciences. The Programme for Human Genomics is a partnership between the Dublin Molecular Medicine Centre (DMMC) comprising UCD & TCD and RCSI's Biopharmaceutical Sciences Network (BSN). This Programme will ultimately create a single Centre of Excellence in Molecular Medicine and Pharmacogenomics. It's over-riding goal is the application of human genomics and proteomics to the study of the pathogenesis, diagnosis and treatment of human disease with a view to identifying new diagnostic markers and therapeutic targets.

The programme has three operational elements:

1. Candidate gene identification through cutting-edge transcriptomic and proteomic research programmes
2. The identification of disease-susceptibility genes by high throughput variant detection, genotyping and gene validation in human disease.
3. The identification of therapeutic targets through state-of-the-art functional genomics, transgenics and gene knockout technologies.

http://www.dmmc.ie/public/itemdetail.cfm?ItemId=93

Call for Biocollection Proposals on the 17-Mar-2004 to 17-Jun-04
The DMMC is committed to the establishment of a number of biological collections that will allow its investigators to test specific research hypotheses. The group charged with deciding which collections are to be given priority have produced a guidance document. Investigators are invited to review this document and revert with proposals for biocollections.

One of the DMMC’s primary objectives is the creation of biological collections that will allow investigators test specific research hypotheses. The DMMC Gene Bank Management Group is charged with deciding which diseases should be included in the initial round of collections under the Programme for Human Genomics. Investigators are invited to consider the guidance contained in the attached consultation document and revert with proposals for collections. Submitting a proposal does not of course mean that you will have to organize the collection itself. If you wish to submit a proposal, please fill out the attached pro-forma and return it to [e-mail].

In this section there is an attached Guidance & Proforma for Proposals which lists diseases that have been initially suggested.

http://www.dmmc.ie/documents/ACF3620%2Edoc

The DMMC Gene Bank Management Group has been charged by the Strategic Management Group with deciding what diseases shoud be included in the initial round of collections for which support has been awarded by HEA under the Programme for Human Genomics.

The target is to collect at least 3000 cases of each disease that is selected for study. This necessarily limits us to diseases that are common enough to generate enough cases in all-Ireland, unless an international collaboration has been established for the disease under study that provides access to a larger catchment population. The selection of what diseases to study will be based upon the criteria listed in the table on the next page. We expect to be able to collect no more than four diseases: one in each of the areas on which the Programme for Human Genomics focuses (neurosciences, vascular biology, inflammation and immunity, cancer)

What has this got to do with the London School of Hygiene & Tropical Medicine? Nothing:

http://www.ucd.ie/govauth/report16.htm

University College Dublin Report from the Governing Authority from its meeting on 18 February 2003

On the recommendations of the assessment board the Authority appointed Dr Stephen Pennington to the Professorship of Proteomics; Dr Desmond Higgins to the Professorship of Bioinformatics; Dr Paul McKeigue to the Professorship of Genetic Epidemiology and Professor Mark Shucksmith to the Professorship of Agricultural Economics and Rural Policy, all subject to ratification by the Academic Council at its next meeting.

Which is why the contact details listed here look a bit odd:

http://www.eudragene.org/

Coordinator: Paul McKeigue <[e-mail]> Professor of Metabolic and Genetic Epidemiology, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, WC1E 7HT, UK

And of course the first two participating centers listed on this site are the London School of Hygiene & Tropical Medicine and University College Dublin.