RespireRx Pharmaceuticals Inc (RSPI)

[myostrain]

This was an interesting read,
3. Investigation into the effects of chronic administration of the novel Ampakines Org 26576 and Org 24448 on functional activity, neurogenesis and receptor/signalling alterations in the murine cerebrum (Chronic administration of Org 26576 (1 mg/kg) and Org 24448 (10 mg/kg) induced functional cerebral increases in the mouse cerebrum particularly in areas of the mesocorticolimbic system, which were not only rapid in onset, with significant effects visible after 7 days administration; but importantly were also persistent and long lasting. These data show that the Ampakines Org 26576 and Org 24448 when administered chronically can potentiate complex neural networks intimately associated with disease states, the effects of which are maintained over prolonged periods.

Persisting and long lasting effects. 10:1 difference b/w 26576 and 24448.


Any thoughts on the possibility of use in patients with TIAs, strokes-recent vs chronic and symptom/location specificity?