Avid Bioservices Inc (CDMO)

[jazzbeerman]

KT,


CMV is a herpes virus. Yes it is an enveloped virus, with exposed PS, which Bavi has been proven to bind.


The majority of us are infected with CMV.


It was actually the most impressive preclinical experiment run by Thorpe & Ran. They ran an "80/20" experiment, (which means they injected enough to kill roughly 80% of the test animals in each of two groups).

One group got 3G4 (Bavituximab).

One group didn't.




In the group that didn't, as expected, roughly 80% died from the CMV infection.

In the "Bavi" group, 100% of the animals survived.





See also the Peregrine Bavi viral "fact sheet" or the PR's discussing the CMV work, or the Thorpe/Ran/King patents discussing same.



- from the PPHM Bavi viral page:

* 100% of animals lethally infected with mouse derived (murine) cytomegalovirus (CMV) and treated with bavituximab survived as compared with 20% survival in control treated animals
* Animals lethally infected with Pichinde virus (a model for Lassa fever, a fatal viral hemorrhagic fever that is on the U.S. government’s biodefense Category A watch list) and then treated with bavituximab showed a 50% survival rate as compared to zero survivors in the control treated group
* Surviving animals infected with Pichinde virus did not show any signs of viral infection several months after treatment with bavituximab and were considered to have been disease free
* Surviving animals had long-term immunity to further infection with the Pichinde virus
* Bavituximab protected lethally infected animals whether treated at the time of viral challenge or after symptoms had developed indicating an active viral infection



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j