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Thursday, 01/10/2008 3:25:18 PM

Thursday, January 10, 2008 3:25:18 PM

Post# of 12660
Interesting article on the possibility of using an oncolytic virus for vaccination: "Adoptive transfer of normal T cells loaded with oncolytic virus into individuals with cancer would be technically easy to implement both to reduce the distribution of metastases and to vaccinate the affected individual in situ against micrometastatic disease. As such, this adoptive transfer could have a great therapeutic impact, in the adjuvant setting, on many different cancer types."
Purging metastases in lymphoid organs using a combination of antigen-nonspecific adoptive T cell therapy, oncolytic virotherapy and immunotherapy
Nature Medicine 14, 37 - 44 (2007)
Published online: 9 December 2007 | doi:10.1038/nm1681
http://www.nature.com/nm/journal/v14/n1/abs/nm1681.html

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