Another scientific article focusing on a compound that inhibits immunotherapy, in this case, by inhibiting the ability of ICAM-1 (CD54) to allow adhesion to endothelium cells. Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy Nature Medicine 14, 28 - 36 (2007) Published online: 6 January 2008 | doi:10.1038/nm1699 http://www.nature.com/nm/journal/v14/n1/abs/nm1699.html "Overexpression of the endothelin B receptor (ETBR) was associated with the absence of TILs and short patient survival time." TILs are tumour infiltrating lymphocytes.
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