Biotech Values

[rancherho]

The current issue of the Journal of Immunology gives great importance to new insights on how T cells and B cells work together in two studies and editorial comments in its Pillars of Immunology section..
“These B cells exposed to a TNP-conjugated carrier, presented the carrier-derived epitopes to carrier specific class II MHC restricted T cells 1000-fold more efficiently than did TNP-specific B cells exposed to an unmodified carrier” Bridging B cell and T cell Recognition of Antigen, PILLARS OF IMMUNOLOGY, J Immunol 2007 179: 7191-7192 http://www.jimmunol.org/current.shtml
Question for any immunologist / scientist: The two studies seem to suggest that a combined antibody reaction and T cell reaction in cancer immunotherapy is substantially more effective than either alone (eg, a hmab and primed T cells against the same antigen may be far superior to either alone or a straight sum of their individual effects). Knowledgeable comments appreciated.