Monday, December 03, 2007 2:37:05 AM
A serious (non-tinhat) question on Dr Hussain's statements.
Dr Husain said both at the meeting and in his letter (I'm paraphrasing here) "I don't see how a drug that doesn't slow progression can have a survival benifit".
The problem with this statement is that he effectively states "Provenge has no benifit wrt progression", and this statement is totally without basis.
It is quite true that the P3 trials did not "prove" (i.e., P<.05) the case that Prov. slowed progression, but it did trend.
Anybody at the meeting stating "Provenge slowed progression" would have been quickly rebuted.
Yet, Dr Hussain said the even more unreasonable "Provenge does not slow progression", and was never questioned.
I'v asked this question before with no response. So if i'm just being an anal idiot on this feel free to slam me
Dr Husain said both at the meeting and in his letter (I'm paraphrasing here) "I don't see how a drug that doesn't slow progression can have a survival benifit".
The problem with this statement is that he effectively states "Provenge has no benifit wrt progression", and this statement is totally without basis.
It is quite true that the P3 trials did not "prove" (i.e., P<.05) the case that Prov. slowed progression, but it did trend.
Anybody at the meeting stating "Provenge slowed progression" would have been quickly rebuted.
Yet, Dr Hussain said the even more unreasonable "Provenge does not slow progression", and was never questioned.
I'v asked this question before with no response. So if i'm just being an anal idiot on this feel free to slam me
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