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Re: microcapfun post# 55503

Sunday, 12/02/2007 3:22:02 AM

Sunday, December 02, 2007 3:22:02 AM

Post# of 253557
>ONXX – How does having a small molecule drug help in the case of macular degeneration? You don't want to treat MD systemically, do you??<

No, you do not. The last company to try a systemic treatment for AMD was GENR, and the program was terminated for lack of enrollment.

Nexavar would presumably have to be modified to increase the half-life if it were to become a serious candidate for treatment of AMD via intravitreal injection.

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