Dendreon Corp fka DNDNQ

[steveporsche]

But isn't the "ratio of normalized events in each arm" what plots the curves? I think I understand the "no events, no improvement in p-value" since over that period with no deaths in both arms you would have two parallel horizontal lines. BTW, Clark have you had a chance to run the simulation models you mentioned in message #4145 - possibly low HR to about 24 to 30 months and good separation thereafter - enrollment ramp as Wall has suggested - overall HR of 1.25 to 1.45 with sensitivities - interim (at 180 deaths) and final analysis p-values based on these assumptions. I wish so much that we could post excel models here to play around with. I have no stats background and had other things on my 19 year old mind when I took stats in college. Your contributions are always appreciated.

Thanks

Steve