Biotech Values

[rancherho]

BSR_David:

>>For active immunos like Provenge that provide a lasting immune response, chemo after may also be effective not because of effects on the T-cell system but because they might pop open cells that release the target antigen and spur a "revitalization" of the immune system response. <<

I recently happened to view the following videa webcast: Modulating Autoimmunity and Tumor Immunity
Wednesday, June 27, 2007
Pamela Sumiko Ohashi, Ph.D., University of Toronto
at: http://videocast.nih.gov/PastEvents.asp?c=28

The presenter detailed a series of experiments to determine what happens to antigens released by cells that undergo apoptosis.The conclusion was that T cells are tolerized to the antigens rather than activated and thereafter may be rapidly deleted in the lymph system.

I suggest that Mitch does more homework.