Biotech Values

[DrBengtP]

Docetaxel before/after Provenge: Is there any synergy?

Docetaxel was approved in May 2004, which is almost 3 years after the last patient was randomized in D9901 (which happened 08 OCT 2001). Thus, the only proven effective treatment became available very late in the study. As for the suggested synergy between Provenge and Docetaxel, isn't it then just so that the very long median survival time for provenge+docetaxel is due to those 2-3 months extra survival that docetaxel gives added ON TOP OF an already long survival time (you have to be a long term survivor in order to get docetaxel)? Consequently, there may not be any synergy whatsoever?

Do we know anything about the use of docetaxel in D9902A?


Thanks!
B.