NOVC Yikes! Ouch! Novacea Ends Drug Study, Citing Deaths Monday November 5, 7:49 am ET Novacea Ends Late-Stage Study of Prostate Cancer Drug Candidate After Unexpected Deaths
SOUTH SAN FRANCISCO, Calif. (AP) -- Biotechnology company Novacea Inc. said Monday it ended a late-stage study of its cancer drug candidate Asentar because of an "imbalance" of deaths. The drug was being developed as a treatment for patients with androgen-independent prostate cancer. Patients received either Asentar with the chemotherapy drug Taxotere or placebo with Taxotere. More than 900 patients were enrolled in the study out of a planned 1,200 patients.
The company said the results were "surprising and disappointing" and that it will further analyze the data to find the possible causes of the deaths.
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