>> Archemix granted a license to Regado for the discovery and development of antidote-controlled aptamers. The REG1 anticoagulation system, which targets Factor IX, completed Phase 1 trials in 2006, the results of which were recently published (Circulation. 2006;114:2490-2497). REG1 is scheduled to begin Phase 2 trials in 2007. <<
Nuvelo is also on record licensing Archemix aptamers to target the coagulation cascade.
I believe Archemix, which announced a strategic alliance with Isis for aptamer development back in August, is planning to to become public.
Aptamers have been around a long time. Maybe the technology is finally advancing beyond the "promising but no products" stage.
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