Dendreon Corp fka DNDNQ

[rancherho]

There recently has been some interesting developments wrt a compound that is apparently synergistic with taxanes and helps them induce apoptosis (cell suicide) on a preferential basis in cancer cells by increasing levels of oxidative stress, which are already quite high in cancer. Although it's being tested in late stage melanoma, there doesn't appear to be any reason that it wouldn't work in other applications where taxanes are being used now. http://www.syntapharma.com/Documents/STA4783_Overview.pdf

SNTA, the developer recently signed a large deal with GSK.http://biz.yahoo.com/bw/071010/20071010005559.html?.v=1

An analyst commented:"In September 2006, Synta reported positive results from a double-blind, randomized, controlled Phase IIb study of 81 patients with malignant melanoma," King said in a note to investors. "This was the first controlled trial in melanoma in 30 years to reach its primary endpoint."
http://biz.yahoo.com/ap/071002/synta_mover.html?.v=1

My comments are not intended as a rec, only that to the extent that the combination of Provenge/GVAX plus Taxotere(docetaxel) may prove to be highly effective, increasing the power of taxanes to kill cancer cells might further increase efficacy in AIPC/HRPC.