Protherics plc (PTIL)

[surf1944]

Protherics PLC announces Notification of Major Interests in Shares


Protherics PLC

Notification of Major Interests in Shares


London, UK; Brentwood, TN, US: 21 August 2007 - Protherics PLC ("Protherics" or
the "Company"), the international biopharmaceutical company focused on critical
care and cancer, announces that on 20 August 2007, in accordance with the
Transparency Obligations Directive, a notification of interest in the ordinary
share capital of the Company was received from AXA Investment Managers UK
Limited on behalf of AXA S.A. and its Group companies ("AXA"). The notification
follows an increase in the Indirect voting rights of AXA from 10.94% to 11.01%
of total voting rights. Details of their interest are as follows: